Leading science, pioneering therapies

Remyelination in multiple sclerosis group publications

2017

Medina-Rodríguez EMaría, Bribián A, Boyd A, Palomo V, Pastor J, Lagares A, Gil C, Martínez A, Williams AC, de Castro F.  2017.  Promoting in vivo remyelination with small molecules: a neuroreparative pharmacological treatment for Multiple Sclerosis.Sci Rep. 7:43545.
Zandee SElizabeth, O'Connor RAnthony, Mair I, Leech MDawn, Williams AC, Anderton SMark.  2017.  IL-10-producing, ST2-expressing Foxp3(+) T cells in multiple sclerosis brain lesions.Immunol Cell Biol.
Dombrowski Y, O'Hagan T, Dittmer M, Penalva R, Mayoral SR, Bankhead P, Fleville S, Eleftheriadis G, Zhao C, Naughton M et al..  2017.  Regulatory T cells promote myelin regeneration in the central nervous system.Nat Neurosci.

2016

Ashworth BEve, Stephens E, Bartlett CA, Serghiou S, Giacci MK, Williams AC, Hart NS, Fitzgerald M.  2016.  Comparative assessment of phototherapy protocols for reduction of oxidative stress in partially transected spinal cord slices undergoing secondary degeneration.BMC Neurosci. 17(1):21.
Ashworth BEve, Stephens E, Bartlett CA, Serghiou S, Giacci MK, Williams AC, Hart NS, Fitzgerald M.  2016.  Comparative assessment of phototherapy protocols for reduction of oxidative stress in partially transected spinal cord slices undergoing secondary degenerationBMC Neuroscience. 17212626147216171520122012536201024123278354024299487230974279401267754940816102902011253227427(1)

2015

Lumley R, Davenport R, Williams AC.  2015.  Most Scottish neurologists do not apply the 2010 McDonald criteria when diagnosing multiple sclerosisThe Journal of the Royal College of Physicians of Edinburgh. 45(1):23-26.
Lindner M, mmler Kü, Arthur A, Brunner S, Elliott C, McElroy D, Mohan H, Williams AC, Edgar JM, Schuh C et al..  2015.  Fibroblast growth factor signalling in multiple sclerosis: inhibition of myelination and induction of pro-inflammatory environment by FGF9Brain. 138(7):1875-1893.
Rittchen S, Boyd A, Burns A, Park J, Fahmy TM, Metcalfe S, Williams AC.  2015.  Myelin repair in vivo is increased by targeting oligodendrocyte precursor cells with nanoparticles encapsulating leukaemia inhibitory factor (LIF).Biomaterials. 56:78-85.
Jarjour AA, Boyd A, Dow LE, Holloway RK, Goebbels S, Humbert PO, Williams AC, ffrench-Constant C.  2015.  The polarity protein scribble regulates myelination and remyelination in the central nervous system.PLoS Biol. 13(3):e1002107.

2014

Münzel E, Becker CG, Becker T, Williams AC.  2014.  Zebrafish regenerate full thickness optic nerve myelin after demyelination, but this fails with increasing age.Acta Neuropathol Commun. 2(1):77.
Williams AC.  2014.  Central nervous system regeneration--where are we?QJM. 107(5):335-9.
Williams AC.  2014.  Response to Letter to Editor from Dr. Walshe.QJM.

2013

Boyd A, Zhang H, Williams AC.  2013.  Insufficient OPC migration into demyelinated lesions is a cause of poor remyelination in MS and mouse models.Acta Neuropathol. 125(6):841-59.
E Münzel J, E Münzel J, Williams AC.  2013.  Promoting remyelination in multiple sclerosis-recent advances.Drugs. 73(18):2017-29.
Münzel EJolanda, Wimperis JZ, Williams AC.  2013.  Relapsing-remitting multiple sclerosis and chronic idiopathic neutropenia: a challenging combination.BMJ Case Rep. 2013
Yuen TJ, Johnson KR, Miron VE, Zhao C, Quandt J, Harrisingh MC, Swire M, Williams AC, McFarland HF, Franklin RJM et al..  2013.  Identification of endothelin 2 as an inflammatory factor that promotes central nervous system remyelination.Brain. 136(Pt 4):1035-47.
Miron VE, Boyd A, Zhao J-W, Yuen TJ, Ruckh JM, Shadrach JL, van Wijngaarden P, Wagers AJ, Williams AC, Franklin RJM et al..  2013.  M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination.Nat Neurosci. 16(9):1211-8.

2012

Münzel EJolanda, Schaefer K, Obirei B, Kremmer E, Burton EA, Kuscha V, Becker CG, Brösamle C, Williams AC, Becker T.  2012.  Claudin k is specifically expressed in cells that form myelin during development of the nervous system and regeneration of the optic nerve in adult zebrafish.Glia. 60(2):253-70.
Wu LMan N, Williams AC, Delaney A, Sherman DL, Brophy PJ.  2012.  Increasing internodal distance in myelinated nerves accelerates nerve conduction to a flat maximum.Curr Biol. 22(20):1957-61.
Jarjour AA, Zhang H, Bauer N, ffrench-Constant C, Williams AC.  2012.  In vitro modeling of central nervous system myelination and remyelination.Glia. 60(1):1-12.

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