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Pluripotent stem cell hepatocyte development group publications

2017

Lucendo-Villarin B, Filis P, Swortwood MJ, Huestis MA, Meseguer-Ripolles J, Cameron K, Iredale JP, O'Shaughnessy PJ, Fowler PA, Hay DC.  2017.  Erratum to: Modelling foetal exposure to maternal smoking using hepatoblasts from pluripotent stem cells.Arch Toxicol.
Lucendo-Villarin B, Filis P, Swortwood MJ, Huestis MA, Meseguer-Ripolles J, Cameron K, Iredale JP, O'Shaughnesy PJ, Fowler PA, Hay DC.  2017.  Modelling foetal exposure to maternal smoking using hepatoblasts from pluripotent stem cells.Arch Toxicol.
Heslop JA, Rowe C, Walsh J, Sison-Young R, Jenkins R, Kamalian L, Kia R, Hay DC, Jones RP, Malik HZ et al..  2017.  Mechanistic evaluation of primary human hepatocyte culture using global proteomic analysis reveals a selective dedifferentiation profile.Arch Toxicol. 91(1):439-452.
Goldring C, Antoine DJ, Bonner F, Crozier J, Denning C, Fontana RJ, Hanley NA, Hay DC, Ingelman-Sundberg M, Juhila S et al..  2017.  Stem cell-derived models to improve mechanistic understanding and prediction of human drug-induced liver injury.Hepatology. 65(2):710-721.
Wang Y, Alhaque S, Cameron K, Meseguer-Ripolles J, Lucendo-Villarin B, Rashidi H, Hay DC.  2017.  Defined and Scalable Generation of Hepatocyte-like Cells from Human Pluripotent Stem Cells.J Vis Exp. (121)

2016

Lucendo-Villarin B, Rashidi H, Cameron K, Hay DC.  2016.  Pluripotent stem cell derived hepatocytes: using materials to define cellular differentiation and tissue engineering.J Mater Chem B Mater Biol Med. 4(20):3433-3442.
Wang Y, Hay DC.  2016.  Mass production of stem cell derived human hepatocytes for experimental medicine.Expert Rev Gastroenterol Hepatol. :1-3.
Szkolnicka D, Lucendo-Villarin B, Moore JK, Simpson KJ, Forbes SJ, Hay DC.  2016.  Reducing Hepatocyte Injury and Necrosis in Response to Paracetamol Using Noncoding RNAs.Stem Cells Transl Med.
Rashidi H., Alhaque S, Szkolnicka D, Flint O, Hay DC.  2016.  Fluid shear stress modulation of hepatocyte-like cell function.Arch Toxicol.
West CC, Hardy WR, Murray IR, James AW, Corselli M, Pang S, Black C, Lobo SE, Sukhija K, Liang P et al..  2016.  Prospective purification of perivascular presumptive mesenchymal stem cells from human adipose tissue: process optimization and cell population metrics across a large cohort of diverse demographics.Stem Cell Res Ther. 7(1):47.
Gow AG, Muirhead R, Hay DC, Argyle DJ.  2016.  Low-Density Lipoprotein Uptake Demonstrates a Hepatocyte Phenotype in the Dog, but Is NonspecificStem Cells and Development. 25(1):90-100.

2015

Cameron K, Tan R, Schmidt-Heck W, Campos G, Lyall MJ, Wang Y, Lucendo-Villarin B, Szkolnicka D, Bates N, Kimber SJ et al..  2015.  Recombinant Laminins Drive the Differentiation and Self-Organization of hESC-Derived Hepatocytes.Stem Cell Reports. 5(6):1250-62.
Palakkan A, Drummond R, Anderson R, Greenhough S, Tv K, Hay DC, Ross J.  2015.  Polarisation and functional characterisation of hepatocytes derived from human embryonic and mesenchymal stem cellsBiomedical Reports.
Heslop J.A, Hammond T.G, Santeramo I., A. Piella T, Hopp I., Zhou J., Baty R., Graziano E.I, B. Marco P, Caron A. et al..  2015.  Concise Review: Workshop Review: Understanding and Assessing the Risks of Stem Cell-Based TherapiesStem Cells Translational Medicine. 4(4):389-400.
Filis P, Nagrath N, Fraser M, Hay DC, Iredale JP, O'Shaughnessy P, Fowler PA.  2015.  Maternal Smoking Dysregulates Protein Expression in Second Trimester Human Fetal Livers in a Sex-Specific MannerThe Journal of Clinical Endocrinology & Metabolism. 100(6):E861-E870.
Godoy P, Schmidt-Heck W, Natarajan K, Lucendo-Villarin B, Szkolnicka D, Asplund A, rquist Pö, Widera A, ber Rö, Campos G et al..  2015.  Gene networks and transcription factor motifs defining the differentiation of stem cells into hepatocyte-like cellsJournal of Hepatology. 63(4):934-942.
Hsieh W.-C., Mackinnon A.C, Lu W.-Y., Jung J., Boulter L., Henderson N.C, Simpson K.J, Schotanus B., Wojtacha D., Bird T.G et al..  2015.  Galectin-3 regulates hepatic progenitor cell expansion during liver injuryGut. 64(2):312-321.
Villarin BLucendo, Cameron K, Szkolnicka D, Rashidi H., Bates N, Kimber SJ, Flint O, Forbes SJ, Iredale JP, Bradley M et al..  2015.  Polyurethane: Stable Cell Phenotype Requires Plasticity: Polymer Supported Directed Differentiation Reveals a Unique Gene Signature Predicting Stable Hepatocyte Performance (Adv. Healthcare Mater. 12/2015).Adv Healthc Mater. 4(12):1819.

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