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Pluripotent stem cell hepatocyte development group publications

2018

Fischer L, Hay DC, O'Farrelly C.  2018.  Innate immunity in stem cell-derived hepatocytes.Philos Trans R Soc Lond B Biol Sci. 373(1750)
Lyall MJ, Cartier J, Thomson JP, Cameron K, Meseguer-Ripolles J, O'Duibhir E, Szkolnicka D, Villarin BLucendo, Wang Y, Blanco GRodriguez et al..  2018.  Modelling non-alcoholic fatty liver disease in human hepatocyte-like cells.Philos Trans R Soc Lond B Biol Sci. 373(1750)
Hagbard L, Cameron K, August P, Penton C, Parmar M, Hay DC, Kallur T.  2018.  Developing defined substrates for stem cell culture and differentiation.Philos Trans R Soc Lond B Biol Sci. 373(1750)
Hay DC, O'Farrelly C.  2018.  Designer human tissue: coming to a lab near you.Philos Trans R Soc Lond B Biol Sci. 373(1750)
Meseguer-Ripolles J, Lucendo-Villarin B, Wang Y, Hay DC.  2018.  Semi-automated Production of Hepatocyte Like Cells from Pluripotent Stem Cells.J Vis Exp. (137)
Rashidi H, Luu N-T, Alwahsh SM, Ginai M, Alhaque S, Dong H, Tomaz RA, Vernay B, Vigneswara V, Hallett JM et al..  2018.  3D human liver tissue from pluripotent stem cells displays stable phenotype in vitro and supports compromised liver function in vivo.Arch Toxicol. 92(10):3117-3129.
Lopez-Yrigoyen M, Fidanza A, Cassetta L, Axton RA, A Taylor H, Meseguer-Ripolles J, Tsakiridis A, Wilson V, Hay DC, Pollard JW et al..  2018.  A human iPSC line capable of differentiating into functional macrophages expressing ZsGreen: a tool for the study and tracking of therapeutic cells.Philos Trans R Soc Lond B Biol Sci. 373(1750)

2017

Lucendo-Villarin B, Filis P, Swortwood MJ, Huestis MA, Meseguer-Ripolles J, Cameron K, Iredale JP, O'Shaughnessy PJ, Fowler PA, Hay DC.  2017.  Erratum to: Modelling foetal exposure to maternal smoking using hepatoblasts from pluripotent stem cells.Arch Toxicol.
Lucendo-Villarin B, Filis P, Swortwood MJ, Huestis MA, Meseguer-Ripolles J, Cameron K, Iredale JP, O'Shaughnesy PJ, Fowler PA, Hay DC.  2017.  Modelling foetal exposure to maternal smoking using hepatoblasts from pluripotent stem cells.Arch Toxicol.
Heslop JA, Rowe C, Walsh J, Sison-Young R, Jenkins R, Kamalian L, Kia R, Hay DC, Jones RP, Malik HZ et al..  2017.  Mechanistic evaluation of primary human hepatocyte culture using global proteomic analysis reveals a selective dedifferentiation profile.Arch Toxicol. 91(1):439-452.
Goldring C, Antoine DJ, Bonner F, Crozier J, Denning C, Fontana RJ, Hanley NA, Hay DC, Ingelman-Sundberg M, Juhila S et al..  2017.  Stem cell-derived models to improve mechanistic understanding and prediction of human drug-induced liver injury.Hepatology. 65(2):710-721.
Wang Y, Alhaque S, Cameron K, Meseguer-Ripolles J, Lucendo-Villarin B, Rashidi H, Hay DC.  2017.  Defined and Scalable Generation of Hepatocyte-like Cells from Human Pluripotent Stem Cells.J Vis Exp. (121)

2016

Lucendo-Villarin B, Rashidi H, Cameron K, Hay DC.  2016.  Pluripotent stem cell derived hepatocytes: using materials to define cellular differentiation and tissue engineering.J Mater Chem B Mater Biol Med. 4(20):3433-3442.
Wang Y, Hay DC.  2016.  Mass production of stem cell derived human hepatocytes for experimental medicine.Expert Rev Gastroenterol Hepatol. :1-3.
Szkolnicka D, Lucendo-Villarin B, Moore JK, Simpson KJ, Forbes SJ, Hay DC.  2016.  Reducing Hepatocyte Injury and Necrosis in Response to Paracetamol Using Noncoding RNAs.Stem Cells Transl Med.
Rashidi H., Alhaque S, Szkolnicka D, Flint O, Hay DC.  2016.  Fluid shear stress modulation of hepatocyte-like cell function.Arch Toxicol.
West CC, Hardy WR, Murray IR, James AW, Corselli M, Pang S, Black C, Lobo SE, Sukhija K, Liang P et al..  2016.  Prospective purification of perivascular presumptive mesenchymal stem cells from human adipose tissue: process optimization and cell population metrics across a large cohort of diverse demographics.Stem Cell Res Ther. 7(1):47.
Gow AG, Muirhead R, Hay DC, Argyle DJ.  2016.  Low-Density Lipoprotein Uptake Demonstrates a Hepatocyte Phenotype in the Dog, but Is NonspecificStem Cells and Development. 25(1):90-100.

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