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Ontogeny of haematopoietic stem cells group publications

2017

McGarvey AC, Rybtsov S, Souilhol C, Tamagno S, Rice R, Hills D, Godwin D, Rice D, Tomlinson SR, Medvinsky A.  2017.  A molecular roadmap of the AGM region reveals BMPER as a novel regulator of HSC maturation.J Exp Med.
Ivanovs A, Rybtsov S, Ng ES, Stanley EG, Elefanty AG, Medvinsky A.  2017.  Human haematopoietic stem cell development: from the embryo to the dish.Development. 144(13):2323-2337.
Redgrave RE, Tual-Chalot S, Davison BJ, Singh E, Hall D, Amirrasouli MM, Gilchrist D, Medvinsky A, Arthur HM.  2017.  Cardiosphere-Derived Cells Require Endoglin for Paracrine-Mediated Angiogenesis.Stem Cell Reports. 8(5):1287-1298.
Batsivari A, Rybtsov S, Souilhol C, Binagui-Casas A, Hills D, Zhao S, Travers P, Medvinsky A.  2017.  Understanding Hematopoietic Stem Cell Development through Functional Correlation of Their Proliferative Status with the Intra-aortic Cluster Architecture.Stem Cell Reports.

2016

Souilhol C, Lendinez JG, Rybtsov S, Murphy F, Wilson H, Hills D, Batsivari A, Binagui-Casas A, McGarvey AC, H MacDonald R et al..  2016.  Developing HSCs become Notch independent by the end of maturation in the AGM region.Blood. 128(12):1567-77.
Ramasamy SK, Kusumbe AP, Schiller M, Zeuschner D, M Bixel G, Milia C, Gamrekelashvili J, Limbourg A, Medvinsky A, Santoro MM et al..  2016.  Blood flow controls bone vascular function and osteogenesis.Nat Commun. 7:13601.
Rybtsov S, Ivanovs A, Zhao S, Medvinsky A.  2016.  Concealed expansion of immature precursors underpins acute burst of adult HSC activity in foetal liver.Development. 143(8):1284-9.
Souilhol C, le Gonneau C, Lendinez JG, Batsivari A, Rybtsov S, Wilson H, Morgado-Palacin L, Hills D, Taoudi S, Antonchuk J et al..  2016.  Inductive interactions mediated by interplay of asymmetric signalling underlie development of adult haematopoietic stem cells.Nat Commun. 7:10784.
Mirantes C, Dosil MAlba, Hills D, Yang J, Eritja N, Santacana M, Gatius S, Vilardell F, Medvinsky A, Matias-Guiu X et al..  2016.  Deletion of Pten in CD45-expressing cells leads to development of T-cell lymphoblastic lymphoma, but not myeloid malignancies.Blood.
Engert A, Balduini C, Brand A, Coiffier B, Cordonnier C, Döhner H, de Wit TDuyvene', Eichinger S, Fibbe W, Green T et al..  2016.  The European Hematology Association Roadmap for European Hematology Research. A Consensus Document.Haematologica.

2015

Economou C, Tsakiridis A, Wymeersch FJ, Gordon-Keylock S, Dewhurst RE, Fisher D, Medvinsky A, Smith AJH, Wilson V.  2015.  Intrinsic factors and the embryonic environment influence the formation of extragonadal teratomas during gestation.BMC Dev Biol. 15(1):35.
Naillat F, Yan W, Karjalainen R, Liakhovitskaia A, Samoylenko A, Xu Q, Sun Z, Shen B, Medvinsky A, Quaggin S et al..  2015.  Identification of the genes regulated by Wnt-4, a critical signal for commitment of the ovary.Exp Cell Res. 332(2):163-78.
Ivanovs A, Medvinsky A.  2015.  In search of human hematopoietic stem cell identity.Cell Stem Cell. 16(1):5-6.
Medvinsky A, Livesey FJ.  2015.  On human development: lessons from stem cell systems.Development. 142(1):17-20.

2014

Potts KS, Sargeant TJ, Markham JF, Shi W, Biben C, Josefsson EC, Whitehead LW, Rogers KL, Liakhovitskaia A, Smyth GK et al..  2014.  A lineage of diploid platelet-forming cells precedes polyploid megakaryocyte formation in the mouse embryo.Blood. 124(17):2725-9.
Rybtsov S, Batsivari A, Bilotkach K, Paruzina D, Senserrich J, Nerushev O, Medvinsky A.  2014.  Tracing the Origin of the HSC Hierarchy Reveals an SCF-Dependent, IL-3-Independent CD43(-) Embryonic Precursor.Stem Cell Reports. 3(3):489-501.
Tarunina M, Hernandez D, Johnson CJ, Rybtsov S, Ramathas V, Jeyakumar M, Watson T, Hook L, Medvinsky A, Mason C et al..  2014.  Directed differentiation of embryonic stem cells using a bead-based combinatorial screening method.PLoS One. 9(9):e104301.
Ivanovs A, Rybtsov S, Anderson RA, Turner ML, Medvinsky A.  2014.  Identification of the niche and phenotype of the first human hematopoietic stem cells.Stem Cell Reports. 2(4):449-56.
Liakhovitskaia A, Rybtsov S, Smith T, Batsivari A, Rybtsova N, Rode C, de Bruijn M, Buchholz F, Gordon-Keylock S, Zhao S et al..  2014.  Runx1 is required for progression of CD41+ embryonic precursors into HSCs but not prior to this.Development. 141(17):3319-23.

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