Leading science, pioneering therapies

Mesoderm and haematopoietic differentiation group publications

2019

Cassetta L, Fragkogianni S, Sims AH, Swierczak A, Forrester LM, Zhang H, Soong DYH, Cotechini T, Anur P, Lin EY et al..  2019.  Human Tumor-Associated Macrophage and Monocyte Transcriptional Landscapes Reveal Cancer-Specific Reprogramming, Biomarkers, and Therapeutic Targets.Cancer Cell.
Lopez-Yrigoyen M, Yang C-T, Fidanza A, Cassetta L, A Taylor H, McCahill A, Sellink E, Von Lindern M, van den Akker E, Mountford JC et al..  2019.  Genetic programming of macrophages generates an in vitro model for the human erythroid island niche.Nat Commun. 10(1):881.

2018

Lopez-Yrigoyen M, Fidanza A, Cassetta L, Axton RA, A Taylor H, Meseguer-Ripolles J, Tsakiridis A, Wilson V, Hay DC, Pollard JW et al..  2018.  A human iPSC line capable of differentiating into functional macrophages expressing ZsGreen: a tool for the study and tracking of therapeutic cells.Philos Trans R Soc Lond B Biol Sci. 373(1750)

2017

Haideri SS, McKinnon AC, A Taylor H, Kirkwood P, Lewis PJStarkey, O'Duibhir E, Vernay B, Forbes SJ, Forrester LM.  2017.  Injection of embryonic stem cell derived macrophages ameliorates fibrosis in a murine model of liver injury.NPJ Regen Med. 2:14.
Fidanza A, Lopez-Yrigoyen M, Romanò N, Jones R, A Taylor H, Forrester LM.  2017.  An all-in-one UniSam vector system for efficient gene activation.Sci Rep. 7(1):6394.
Haideri SS, McKinnon AC, A. Taylor H, Kirkwood P, Lewis PJStarkey, O'Duibhir E, Vernay B, Forbes SJ, Forrester LM.  2017.  Injection of embryonic stem cell derived macrophages ameliorates fibrosis in a murine model of liver injurynpj Regenerative Medicine. 2201345340533010911011514617385458833621119117633130(1)
Axton RA, Haideri SS, Lopez-Yrigoyen M, Taylor HA, Forrester LM.  2017.  SplitAx: A novel method to assess the function of engineered nucleases.PLoS One. 12(2):e0171698.

2016

Jackson M, Ma R, A Taylor H, Axton RA, Easterbrook J, Kydonaki M, Olivier E, Marenah L, Stanley EG, Elefanty AG et al..  2016.  Enforced Expression of HOXB4 in Human Embryonic Stem Cells Enhances the Production of Hematopoietic Progenitors but Has No Effect on the Maturation of Red Blood Cells.Stem Cells Transl Med. 5(8):981-90.
Yang C-T, Ma R, Axton RA, Jackson M, A Taylor H, Fidanza A, Marenah L, Frayne J, Mountford JC, Forrester LM.  2016.  Activation of KLF1 Enhances the Differentiation and Maturation of Red Blood Cells from Human Pluripotent Stem Cells.Stem Cells.
Easterbrook J, Fidanza A, Forrester LM.  2016.  Concise review: programming human pluripotent stem cells into blood.Br J Haematol.
Easterbrook J, Fidanza A, Forrester LM.  2016.  Concise review: programming human pluripotent stem cells into bloodBritish Journal of Haematology. :n/a-n/a.
Engert A, Balduini C, Brand A, Coiffier B, Cordonnier C, Döhner H, de Wit TDuyvene', Eichinger S, Fibbe W, Green T et al..  2016.  The European Hematology Association Roadmap for European Hematology Research. A Consensus Document.Haematologica.

2015

Arner E., Daub C.O, Vitting-Seerup K., Andersson R., Lilje B., Drablos F., Lennartsson A., Ronnerblad M., Hrydziuszko O., Vitezic M. et al..  2015.  Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cellsScience. 347(6225):1010-1014.
Yeung A.TY, Hale C., Xia J., Tate P.H, Goulding D., Keane J.A, Mukhopadhyay S., Forrester LM, Billker O., Skarnes W.C et al..  2015.  Conditional-ready mouse embryonic stem cell derived macrophages enable the study of essential genes in macrophage functionScientific Reports. 5:8908.
Kara M, Axton RA, Jackson M, Ghaffari S, Buerger K, Watt AJ, A Taylor H, Orr B, Hardy WR, Péault B et al..  2015.  A role for mospd1 in mesenchymal stem cell proliferation and differentiation.Stem Cells.

2013

Huang C, Jackson M, Samuel K, A Taylor H, Lowell S, Forrester LM.  2013.  Haematopoietic differentiation is inhibited when Notch activity is enhanced in FLK1(+) mesoderm progenitors.Stem Cell Res. 11(3):1273-87.
Rog-Zielinska EA, Thomson A, Kenyon CJ, Brownstein DG, Moran CM, Szumska D, Michailidou Z, Richardson J, Owen E, Watt A et al..  2013.  Glucocorticoid receptor is required for foetal heart maturation.Hum Mol Genet. 22(16):3269-82.

2012

Forrester LM, Jackson M.  2012.  Mechanism of action of HOXB4 on the hematopoietic differentiation of embryonic stem cells.Stem Cells. 30(3):379-85.
Agarwal S, Sebastian A, Forrester LM, Markx GH.  2012.  Formation of embryoid bodies using dielectrophoresis.Biomicrofluidics. 6(2):24101-2410111.

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