Leading science, pioneering therapies

Embryonic stem cell differentiation group publications

2017

Burute M, Prioux M, Blin G, Truchet S, Letort G, Tseng Q, Bessy T, Lowell S, Young J, Filhol O et al..  2017.  Polarity Reversal by Centrosome Repositioning Primes Cell Scattering during Epithelial-to-Mesenchymal Transition.Dev Cell. 40(2):168-184.

2016

Qiu J, McQueen J, Bilican B, Dando O, Magnani D, Punovuori K, Selvaraj BT, Livesey M, Haghi G, Heron S et al..  2016.  Evidence for evolutionary divergence of activity-dependent gene expression in developing neurons.Elife. 5

2015

Laing AF, Lowell S, Brickman JM.  2015.  Gro/TLE enables embryonic stem cell differentiation by repressing pluripotent gene expression.Dev Biol. 397(1):56-66.

2014

Tsakiridis A, Huang Y, Blin G, Skylaki S, Wymeersch FJ, Osorno R, Economou C, Karagianni E, Zhao S, Lowell S et al..  2014.  Distinct Wnt-driven primitive streak-like populations reflect in vivo lineage precursors.Development. 141(6):1209-21.

2013

Huang C, Jackson M, Samuel K, A Taylor H, Lowell S, Forrester LM.  2013.  Haematopoietic differentiation is inhibited when Notch activity is enhanced in FLK1(+) mesoderm progenitors.Stem Cell Res. 11(3):1273-87.
Lowell S.  2013.  Getting the measure of things: the physical biology of stem cells.Development. 140(20):4125-8.
Malaguti M, Nistor PA, Blin G, Pegg A, Zhou X, Lowell S.  2013.  Bone morphogenic protein signalling suppresses differentiation of pluripotent cells by maintaining expression of E-Cadherin.Elife. 2:e01197.
Davies OR, Lin C-Y, Radzisheuskaya A, Zhou X, Taube J, Blin G, Waterhouse A, Smith AJH, Lowell S.  2013.  Tcf15 primes pluripotent cells for differentiation.Cell Rep. 3(2):472-84.
Zhou X, Smith AJH, Waterhouse A, Blin G, Malaguti M, Lin C-Y, Osorno R, Chambers I, Lowell S.  2013.  Hes1 desynchronizes differentiation of pluripotent cells by modulating STAT3 activity.Stem Cells. 31(8):1511-22.

2012

Boulter L, Govaere O, Bird TG, Radulescu S, Ramachandran P, Pellicoro A, Ridgway RA, Seo SSoo, Spee B, van Rooijen N et al..  2012.  Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease.Nat Med. 18(4):572-9.

2006

Lowell S, Benchoua A, Heavey B, Smith AG.  2006.  Notch promotes neural lineage entry by pluripotent embryonic stem cells.PLoS Biol. 4(5):e121.
Lowell S.  2006.  Stem cells in the genomic age.Genome Biol. 7(5):315.
Pollard SM, Benchoua A, Lowell S.  2006.  Neural stem cells, neurons, and glia.Methods Enzymol. 418:151-69.

2003

Gabay L, Lowell S, Rubin LL, Anderson DJ.  2003.  Deregulation of dorsoventral patterning by FGF confers trilineage differentiation capacity on CNS stem cells in vitro.Neuron. 40(3):485-99.

2002

Janes SM, Lowell S, Hutter C.  2002.  Epidermal stem cells.J Pathol. 197(4):479-91.

2001

Lowell S, Watt FM.  2001.  Delta regulates keratinocyte spreading and motility independently of differentiation.Mech Dev. 107(1-2):133-40.

2000

Lowell S, Jones P, Le Roux I, Dunne J, Watt FM.  2000.  Stimulation of human epidermal differentiation by delta-notch signalling at the boundaries of stem-cell clusters.Curr Biol. 10(9):491-500.
Lowell S.  2000.  Stem cells: You make me feel so glial.Curr Biol. 10(16):R595-7.

1999

Jensen UB, Lowell S, Watt FM.  1999.  The spatial relationship between stem cells and their progeny in the basal layer of human epidermis: a new view based on whole-mount labelling and lineage analysis.Development. 126(11):2409-18.
Printer-friendly versionPrinter-friendly version