Leading science, pioneering therapies

Early embryo development group publications

2018

Frith, Jr T, Granata I, Wind M, Stout E, Thompson O, Neumann K, Stavish D, Heath PR, Ortmann D, Hackland JOs et al..  2018.  Human axial progenitors generate trunk neural crest cells in vitro.Elife. 7
Row RH, Pegg A, Kinney BA, Farr GH, Maves L, Lowell S, Wilson V, Martin BL.  2018.  BMP and FGF signaling interact to pattern mesoderm by controlling basic helix-loop-helix transcription factor activity.Elife. 7
Lopez-Yrigoyen M, Fidanza A, Cassetta L, Axton RA, A Taylor H, Meseguer-Ripolles J, Tsakiridis A, Wilson V, Hay DC, Pollard JW et al..  2018.  A human iPSC line capable of differentiating into functional macrophages expressing ZsGreen: a tool for the study and tracking of therapeutic cells.Philos Trans R Soc Lond B Biol Sci. 373(1750)
Tosti L, Ashmore J, Tan BSiang Nich, Carbone B, Mistri TK, Wilson V, Tomlinson SR, Kaji K.  2018.  Mapping transcription factor occupancy using minimal numbers of cells in vitro and in vivo.Genome Res. 28(4):592-605.

2017

Corsinotti A, Wong FCk, Tatar T, Szczerbinska I, Halbritter F, Colby D, Gogolok S, Pantier R, Liggat K, Mirfazeli ES et al..  2017.  Distinct SoxB1 networks are required for naïve and primed pluripotency.Elife. 6
Gouti M, Delile J, Stamataki D, Wymeersch FJ, Huang Y, Kleinjung J, Wilson V, Briscoe J.  2017.  A Gene Regulatory Network Balances Neural and Mesoderm Specification during Vertebrate Trunk Development.Dev Cell. 41(3):243-261.e7.

2016

Castillo S.D, Tzouanacou E., Zaw-Thin M., Berenjeno I.M, Parker V.ER, Chivite I., Mila-Guasch M., Pearce W., Solomon I., Angulo-Urarte A. et al..  2016.  Somatic activating mutations in Pik3ca cause sporadic venous malformations in mice and humansScience Translational Medicine. 8(332):332ra43-332ra43.
Wymeersch FJ, Huang Y, Blin G, Cambray N, Wilkie R, Wong FCk, Wilson V.  2016.  Position-dependent plasticity of distinct progenitor types in the primitive streak.Elife. 5

2015

Tsakiridis A, Wilson V.  2015.  Assessing the bipotency of in vitro-derived neuromesodermal progenitors.F1000Res. 4:100.
Economou C, Tsakiridis A, Wymeersch FJ, Gordon-Keylock S, Dewhurst RE, Fisher D, Medvinsky A, Smith AG, Wilson V.  2015.  Intrinsic factors and the embryonic environment influence the formation of extragonadal teratomas during gestation.BMC Dev Biol. 15(1):35.

2014

Gouti M, Tsakiridis A, Wymeersch FJ, Huang Y, Kleinjung J, Wilson V, Briscoe J.  2014.  In vitro generation of neuromesodermal progenitors reveals distinct roles for wnt signalling in the specification of spinal cord and paraxial mesoderm identity.PLoS Biol. 12(8):e1001937.
Tsakiridis A, Huang Y, Blin G, Skylaki S, Wymeersch FJ, Osorno R, Economou C, Karagianni E, Zhao S, Lowell S et al..  2014.  Distinct Wnt-driven primitive streak-like populations reflect in vivo lineage precursors.Development. 141(6):1209-21.

2013

Huang C-J, Wilson V, Pennings S, MacRae CA, Mullins JJ.  2013.  Sequential effects of spadetail, one-eyed pinhead and no tail on midline convergence of nephric primordia during zebrafish embryogenesis.Dev Biol. 384(2):290-300.
Festuccia N, Osorno R, Wilson V, Chambers I.  2013.  The role of pluripotency gene regulatory network components in mediating transitions between pluripotent cell states.Curr Opin Genet Dev. 23(5):504-11.

2012

Huang Y, Osorno R, Tsakiridis A, Wilson V.  2012.  In Vivo differentiation potential of epiblast stem cells revealed by chimeric embryo formation.Cell Rep. 2(6):1571-8.
Osorno R, Tsakiridis A, Wong F, Cambray N, Economou C, Wilkie R, Blin G, Scotting PJ, Chambers I, Wilson V.  2012.  The developmental dismantling of pluripotency is reversed by ectopic Oct4 expression.Development. 139(13):2288-98.

2011

Lindvall O, Kokaia Z, Wilson V.  2011.  Creation of human-animal entities for translational stem cell research: Scientific explanation of issues that are often confusedTranslational Stem Cell Research: Issues Beyond the Debate on the Moral Status of the Human Embryo. :3-14.

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