Leading science, pioneering therapies

Adult tissue cell plasticity, reprogramming, fate change and regeneration group publications

2015

2014

Rambukkana A, Masaki T.  2014.  Neurodegeneration in leprosy: Insights from model systems and patientsNeglected Tropical Diseases and Conditions of the Nervous System.
Truman RW, Ebenezer GJ, Pena MT, Sharma R, Balamayooran G, Gillingwater TH, Scollard DM, McArthur JC, Rambukkana A.  2014.  The armadillo as a model for peripheral neuropathy in leprosy.ILAR J. 54(3):304-14.
Masaki T, McGlinchey A, Cholewa-Waclaw J, Qu J, Tomlinson SR, Rambukkana A.  2014.  Innate immune response precedes Mycobacterium leprae-induced reprogramming of adult Schwann cells.Cell Reprogram. 16(1):9-17.

2013

Masaki T, Qu J, Cholewa-Waclaw J, Burr K, Raaum R, Rambukkana A.  2013.  Reprogramming adult Schwann cells to stem cell-like cells by leprosy bacilli promotes dissemination of infection.Cell. 152(1-2):51-67.

2011

Takatsuka M, Osada-Oka M, Satoh EF, Kitadokoro K, Nishiuchi Y, Niki M, Inoue M, Iwai K, Arakawa T, Shimoji Y et al..  2011.  A histone-like protein of mycobacteria possesses ferritin superfamily protein-like activity and protects against DNA damage by Fenton reaction.PLoS One. 6(6):e20985.

2010

2006

Tapinos N, Ohnishi M, Rambukkana A.  2006.  ErbB2 receptor tyrosine kinase signaling mediates early demyelination induced by leprosy bacilli.Nat Med. 12(8):961-6.
Im JS, Tapinos N, Chae G-T, Illarionov PA, Besra GS, DeVries GH, Modlin RL, Sieling PA, Rambukkana A, Porcelli SA.  2006.  Expression of CD1d molecules by human schwann cells and potential interactions with immunoregulatory invariant NK T cells.J Immunol. 177(8):5226-35.

2005

2004

Rambukkana A.  2004.  Mycobacterium leprae-induced demyelination: a model for early nerve degeneration.Curr Opin Immunol. 16(4):511-8.

2003

Rambukkana A, Kunz S, Min J, Campbell KP, Oldstone MBA.  2003.  Targeting Schwann cells by nonlytic arenaviral infection selectively inhibits myelination.Proc Natl Acad Sci U S A. 100(26):16071-6.
Oliveira RB, Ochoa MT, Sieling PA, Rea TH, Rambukkana A, Sarno EN, Modlin RL.  2003.  Expression of Toll-like receptor 2 on human Schwann cells: a mechanism of nerve damage in leprosy.Infect Immun. 71(3):1427-33.

2002

Rambukkana A, Zanazzi G, Tapinos N, Salzer JL.  2002.  Contact-dependent demyelination by Mycobacterium leprae in the absence of immune cells.Science. 296(5569):927-31.

2001

Rambukkana A.  2001.  M. leprae genome sequence.Trends Microbiol. 9(4):157.
Rambukkana A.  2001.  Molecular basis for the peripheral nerve predilection of Mycobacterium leprae.Curr Opin Microbiol. 4(1):21-7.

2000

Rambukkana A.  2000.  How does Mycobacterium leprae target the peripheral nervous system?Trends Microbiol. 8(1):23-8.
Ng V, Zanazzi G, Timpl R, Talts JF, Salzer JL, Brennan PJ, Rambukkana A.  2000.  Role of the cell wall phenolic glycolipid-1 in the peripheral nerve predilection of Mycobacterium leprae.Cell. 103(3):511-24.

1999

Shimoji Y, Ng V, Matsumura K, Fischetti VA, Rambukkana A.  1999.  A 21-kDa surface protein of Mycobacterium leprae binds peripheral nerve laminin-2 and mediates Schwann cell invasion.Proc Natl Acad Sci U S A. 96(17):9857-62.

Pages