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Derivation of the clinical grade human embryonic stem cell line RCe021-A (RC-17).

TitleDerivation of the clinical grade human embryonic stem cell line RCe021-A (RC-17).
Publication TypeJournal Article
Year of Publication2016
Authorsde Sousa PA, Tye BJ, Bruce K, Dand P, Russell G, Collins DM, Greenshields A, McDonald K, Bradburn H, Allan D, Laurie A, Kunath T, Canham MA, Downie JM, Bateman M, Courtney A
JournalStem Cell Res
Volume17
Issue1
Pagination1-5
Date Published2016 Apr 30
ISSN1876-7753
Abstract

The human embryonic stem cell line RCe021-A (RC-17) was derived under quality assured compliance with UK regulation, European Union Directives and International guidance for tissue procurement, processing and storage according to Good Manufacturing Practice (GMP) standards. The cell line was derived from a day 3 embryo voluntarily donated as unsuitable or surplus to fertility requirements following informed consent. RCe021-A (RC-17) shows normal pluripotency marker expression and differentiation to the three germ layers in vitro. It has a normal 46XX female karyotype and microsatellite PCR identity, HLA and blood group typing data are available.

DOI10.1016/j.scr.2016.04.019
Alternate JournalStem Cell Res
PubMed ID27558596
Publication institute
CRM