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Current trends in bone tissue engineering.

TitleCurrent trends in bone tissue engineering.
Publication TypeJournal Article
Year of Publication2014
AuthorsMravic M, Péault B, James AW
JournalBiomed Res Int
Volume2014
Pagination865270
Date Published2014
ISSN2314-6141
Abstract

The development of tissue engineering and regeneration constitutes a new platform for translational medical research. Effective therapies for bone engineering typically employ the coordinated manipulation of cells, biologically active signaling molecules, and biomimetic, biodegradable scaffolds. Bone tissue engineering has become increasingly dependent on the merging of innovations from each of these fields, as they continue to evolve independently. This foreword will highlight some of the most recent advances in bone tissue engineering and regeneration, emphasizing the interconnected fields of stem cell biology, cell signaling biology, and biomaterial research. These include, for example, novel methods for mesenchymal stem cell purification, new methods of Wnt signaling pathway manipulation, and cutting edge computer assisted nanoscale design of bone scaffold materials. In the following special issue, we sought to incorporate these diverse areas of emphasis in order to reflect current trends in the field.

DOI10.1155/2014/865270
Alternate JournalBiomed Res Int
PubMed ID24804256
PubMed Central IDPMC3997160
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