Leading science, pioneering therapies

CRM Publications

Found 17 results
Filters: Keyword is Genome  [Clear All Filters]
2014
Williamson I, Berlivet S, Eskeland R, Boyle S, Illingworth R, Paquette D, Dostie J, Bickmore WA.  2014.  Spatial genome organization: contrasting views from chromosome conformation capture and fluorescence in situ hybridization.Genes Dev. 28(24):2778-91.
2013
de Wit E, Bouwman BAM, Zhu Y, Klous P, Splinter E, Verstegen MJAM, Krijger PHL, Festuccia N, Nora EP, Welling M et al..  2013.  The pluripotent genome in three dimensions is shaped around pluripotency factors.Nature. 501(7466):227-31.
Soufi A, Zaret KS.  2013.  Understanding impediments to cellular conversion to pluripotency by assessing the earliest events in ectopic transcription factor binding to the genome.Cell Cycle. 12(10):1487-91.
2012
Skylaki S, Tomlinson SR.  2012.  Recurrent transcriptional clusters in the genome of mouse pluripotent stem cells.Nucleic Acids Res. 40(19):e153.
2011
Deaton AM, Webb S, Kerr ARW, Illingworth R, Guy J, Andrews R, Bird A.  2011.  Cell type-specific DNA methylation at intragenic CpG islands in the immune system.Genome Res. 21(7):1074-86.
2010
Thomson JP, Skene PJ, Selfridge J, Clouaire T, Guy J, Webb S, Kerr ARW, Deaton A, Andrews R, James KD et al..  2010.  CpG islands influence chromatin structure via the CpG-binding protein Cfp1.Nature. 464(7291):1082-6.
Hanina SA, Mifsud W, Down TA, Hayashi K, O'Carroll D, Lao K, Miska EA, M Surani A.  2010.  Genome-wide identification of targets and function of individual MicroRNAs in mouse embryonic stem cells.PLoS Genet. 6(10):e1001163.
Skene PJ, Illingworth R, Webb S, Kerr ARW, James KD, Turner DJ, Andrews R, Bird AP.  2010.  Neuronal MeCP2 is expressed at near histone-octamer levels and globally alters the chromatin state.Mol Cell. 37(4):457-68.
Illingworth R, Gruenewald-Schneider U, Webb S, Kerr ARW, James KD, Turner DJ, Smith C, Harrison DJ, Andrews R, Bird AP.  2010.  Orphan CpG islands identify numerous conserved promoters in the mammalian genome.PLoS Genet. 6(9):e1001134.
2009
Jacobs FMJ, van Erp S, van der Linden AJA, von Oerthel L, J Burbach PH, Smidt MP.  2009.  Pitx3 potentiates Nurr1 in dopamine neuron terminal differentiation through release of SMRT-mediated repression.Development. 136(4):531-40.
2007
Wallace HAC, Marques-Kranc F, Richardson M, Luna-Crespo F, Sharpe JA, Hughes J, Wood WG, Higgs DR, Smith AG.  2007.  Manipulating the mouse genome to engineer precise functional syntenic replacements with human sequence.Cell. 128(1):197-209.
2006
Robertson M, Stenhouse FH, Colby D, Marland JRK, Nichols J, Tweedie S, Chambers I.  2006.  Nanog retrotransposed genes with functionally conserved open reading frames.Mamm Genome. 17(7):732-43.
2004
Pals P, Lincoln S, Manning JR, Heckman M, Skipper L, Hulihan M, Van den Broeck M, De Pooter T, Cras P, Crook J et al..  2004.  alpha-Synuclein promoter confers susceptibility to Parkinson's disease.Ann Neurol. 56:591–595.
2003
Testa G, Zhang Y, Vintersten K, Benes V, Pijnappel WWMPim, Chambers I, Smith AG, Smith AG, A Stewart F.  2003.  Engineering the mouse genome with bacterial artificial chromosomes to create multipurpose alleles.Nat Biotechnol. 21(4):443-7.
2001
Peters AH, O'Carroll D, Scherthan H, Mechtler K, Sauer S, Schöfer C, Weipoltshammer K, Pagani M, Lachner M, Kohlmaier A et al..  2001.  Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability.Cell. 107(3):323-37.
2000
Cheadle JP, Dobbie L, Idziaszczyk S, Hodges AK, Smith AG, Sampson JR, Young J.  2000.  Genomic organization and comparative analysis of the mouse tuberous sclerosis 1 (Tsc1) locus.Mamm Genome. 11(12):1135-8.
1996
Sam M, Wurst W, Forrester LM, Vauti F, Heng H, Bernstein A.  1996.  A novel family of repeat sequences in the mouse genome responsive to retinoic acid.Mamm Genome. 7(10):741-8.