Leading science, pioneering therapies

CRM Publications

Found 21 results
Filters: Keyword is Multiple Sclerosis  [Clear All Filters]
2017
Choileain SNi, Hay J, Thomas J, Williams AC, Vermeren MM, Benezech C, Gomez-Salazar M, Hugues OR, Vermeren S, Howie SEM et al..  2017.  TCR-stimulated changes in cell surface CD46 expression generate type 1 regulatory T cells.Sci Signal. 10(502)
2015
Vesterinen HM, Connick P, Irvine CMJ, Sena ES, Egan KJ, Carmichael GG, Tariq A, Pavitt S, Chataway J, Macleod MR et al..  2015.  Drug repurposing: a systematic approach to evaluate candidate oral neuroprotective interventions for secondary progressive multiple sclerosis.PLoS One. 10(4):e0117705.
2014
Foley P, Lawler A, Chandran S, Mead G.  2014.  Potential disease-modifying effects of selective serotonin reuptake inhibitors in multiple sclerosis: systematic review and meta-analysis.J Neurol Neurosurg Psychiatry. 85(6):709-10.
Hunt DPJ, Kavanagh D, Drummond I, Weller B, Bellamy C, Overell J, Evans S, Jackson A, Chandran S.  2014.  Thrombotic microangiopathy associated with interferon beta.N Engl J Med. 370(13):1270-1.
2013
Stoffels JMJ, de Jonge JC, Stancic M, Nomden A, van Strien ME, Ma D, Sisková Z, Maier O, ffrench-Constant C, Franklin RJM et al..  2013.  Fibronectin aggregation in multiple sclerosis lesions impairs remyelination.Brain. 136(Pt 1):116-31.
Boyd A, Zhang H, Williams AC.  2013.  Insufficient OPC migration into demyelinated lesions is a cause of poor remyelination in MS and mouse models.Acta Neuropathol. 125(6):841-59.
Foley PL, Vesterinen HM, Laird BJ, Sena ES, Colvin LA, Chandran S, Macleod MR, Fallon MT.  2013.  Prevalence and natural history of pain in adults with multiple sclerosis: systematic review and meta-analysis.Pain. 154(5):632-42.
2012
Franklin RJM, ffrench-Constant C, Edgar JM, Smith KJ.  2012.  Neuroprotection and repair in multiple sclerosis.Nat Rev Neurol. 8(11):624-34.
2011
Stankoff B, Freeman L, Aigrot M-S, Chardain A, Dollé F, Williams AC, Galanaud D, Armand L, Lehericy S, Lubetzki C et al..  2011.  Imaging central nervous system myelin by positron emission tomography in multiple sclerosis using [methyl-¹¹C]-2-(4'-methylaminophenyl)- 6-hydroxybenzothiazole.Ann Neurol. 69(4):673-80.
Huang JK, Fancy SPJ, Zhao C, Rowitch DH, ffrench-Constant C, Franklin RJM.  2011.  Myelin regeneration in multiple sclerosis: targeting endogenous stem cells.Neurotherapeutics. 8(4):650-8.
Huang JK, Jarjour AA, Oumesmar BNait, Kerninon C, Williams AC, Krezel W, Kagechika H, Bauer J, Zhao C, Van Evercooren ABaron- et al..  2011.  Retinoid X receptor gamma signaling accelerates CNS remyelination.Nat Neurosci. 14(1):45-53.
Huang JK, Jarjour AA, ffrench-Constant C, Franklin RJM.  2011.  Retinoid X receptors as a potential avenue for regenerative medicine in multiple sclerosis.Expert Rev Neurother. 11(4):467-8.
2010
Vesterinen HM, Sena ES, ffrench-Constant C, Williams AC, Chandran S, Macleod MR.  2010.  Improving the translational hit of experimental treatments in multiple sclerosis.Mult Scler. 16(9):1044-55.
Franklin RJM, ffrench-Constant C.  2010.  Stem cell treatments and multiple sclerosis.BMJ. 340:c1387.
2009
Anderson JMarian, Patani R, Reynolds R, Nicholas R, Compston A, Spillantini MGrazia, Chandran S.  2009.  Evidence for abnormal tau phosphorylation in early aggressive multiple sclerosis.Acta Neuropathol. 117(5):583-9.
Bauer NG, ffrench-Constant C.  2009.  Physical forces in myelination and repair: a question of balance?J Biol. 8(8):78.
Harkiolaki M, Holmes SL, Svendsen P, Gregersen JW, Jensen LT, McMahon R, Friese MA, van Boxel G, Etzensperger R, Tzartos JS et al..  2009.  T cell-mediated autoimmune disease due to low-affinity crossreactivity to common microbial peptides.Immunity. 30(3):348-57.
2008
Chandran S, Hunt DPJ, Joannides A, Zhao C, Compston A, Franklin RJM.  2008.  Myelin repair: the role of stem and precursor cells in multiple sclerosis.Philos Trans R Soc Lond B Biol Sci. 363(1489):171-83.
2006
Gregersen JW, Kranc KR, Ke X, Svendsen P, Madsen LS, Thomsen ARandrup, Cardon LR, Bell JI, Fugger L.  2006.  Functional epistasis on a common MHC haplotype associated with multiple sclerosis.Nature. 443(7111):574-7.
2005
Kranc KR, Taylor AM, Willcox N, Fugger L.  2005.  Control of autoimmunity by "epitope theft".Trends Mol Med. 11(1):1-4.
2003
Zarei M, Chandran S, Compston A, Hodges J.  2003.  Cognitive presentation of multiple sclerosis: evidence for a cortical variant.J Neurol Neurosurg Psychiatry. 74(7):872-7.