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Found 28 results
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2017
McGarvey AC, Rybtsov S, Souilhol C, Tamagno S, Rice R, Hills D, Godwin D, Rice D, Tomlinson SR, Medvinsky A.  2017.  A molecular roadmap of the AGM region reveals BMPER as a novel regulator of HSC maturation.J Exp Med. 214(12):3731-3751.
2014
Imanirad P, Kartalaei PSolaimani, Crisan M, Vink C, Yamada-Inagawa T, de Pater E, Kurek D, Kaimakis P, van der Linden R, Speck N et al..  2014.  HIF1α is a regulator of hematopoietic progenitor and stem cell development in hypoxic sites of the mouse embryo.Stem Cell Res. 12(1):24-35.
2013
Mirshekar-Syahkal B, Haak E, Kimber GM, van Leusden K, Harvey K, O'Rourke J, Laborda J, Bauer SR, de Bruijn MFTR, Ferguson-Smith AC et al..  2013.  Dlk1 is a negative regulator of emerging hematopoietic stem and progenitor cells.Haematologica. 98(2):163-71.
2012
Fitch SR, Kimber GM, Wilson NK, Parker A, Mirshekar-Syahkal B, Göttgens B, Medvinsky A, Dzierzak E, Ottersbach K.  2012.  Signaling from the sympathetic nervous system regulates hematopoietic stem cell emergence during embryogenesis.Cell Stem Cell. 11(4):554-66.
2011
Robin C, Ottersbach K, Boisset J-C, Oziemlak A, Dzierzak E.  2011.  CD41 is developmentally regulated and differentially expressed on mouse hematopoietic stem cells.Blood. 117(19):5088-91.
Rybtsov S, Sobiesiak M, Taoudi S, Souilhol C, Senserrich J, Liakhovitskaia A, Ivanovs A, Frampton J, Zhao S, Medvinsky A.  2011.  Hierarchical organization and early hematopoietic specification of the developing HSC lineage in the AGM region.J Exp Med. 208(6):1305-15.
Ivanovs A, Rybtsov S, Welch L, Anderson RA, Turner ML, Medvinsky A.  2011.  Highly potent human hematopoietic stem cells first emerge in the intraembryonic aorta-gonad-mesonephros region.J Exp Med. 208(12):2417-27.
2010
Taylor E, Taoudi S, Medvinsky A.  2010.  Hematopoietic stem cell activity in the aorta-gonad-mesonephros region enhances after mid-day 11 of mouse development.Int J Dev Biol. 54(6-7):1055-60.
Gordon-Keylock S, Jackson M, Huang C, Samuel K, Axton RA, Oostendorp RAJ, A Taylor H, Wilson J, Forrester LM.  2010.  Induction of hematopoietic differentiation of mouse embryonic stem cells by an AGM-derived stromal cell line is not further enhanced by overexpression of HOXB4.Stem Cells Dev. 19(11):1687-98.
He W, Nieponice A, Soletti L, Hong Y, Gharaibeh B, Crisan M, Usas A, Péault B, Huard J, Wagner WR et al..  2010.  Pericyte-based human tissue engineered vascular grafts.Biomaterials. 31(32):8235-44.
2009
Bee T, Liddiard K, Swiers G, Bickley SRB, Vink CS, Jarratt A, Hughes J, Medvinsky A, de Bruijn MFTR.  2009.  Alternative Runx1 promoter usage in mouse developmental hematopoiesis.Blood Cells Mol Dis. 43(1):35-42.
Mascarenhas MI, Parker A, Dzierzak E, Ottersbach K.  2009.  Identification of novel regulators of hematopoietic stem cell development through refinement of stem cell localization and expression profiling.Blood. 114(21):4645-53.
Peeters M, Ottersbach K, Bollerot K, Orelio C, de Bruijn M, Wijgerde M, Dzierzak E.  2009.  Ventral embryonic tissues and Hedgehog proteins induce early AGM hematopoietic stem cell development.Development. 136(15):2613-21.
2007
Durand C, Robin C, Bollerot K, Baron MH, Ottersbach K, Dzierzak E.  2007.  Embryonic stromal clones reveal developmental regulators of definitive hematopoietic stem cells.Proc Natl Acad Sci U S A. 104(52):20838-43.
Taoudi S, Medvinsky A.  2007.  Functional identification of the hematopoietic stem cell niche in the ventral domain of the embryonic dorsal aorta.Proc Natl Acad Sci U S A. 104(22):9399-403.
2006
Krassowska A, Gordon-Keylock S, Samuel K, Gilchrist D, Dzierzak E, Oostendorp R, Forrester LM, Ansell JD.  2006.  Promotion of haematopoietic activity in embryonic stem cells by the aorta-gonad-mesonephros microenvironment.Exp Cell Res. 312(18):3595-603.
Robin C, Ottersbach K, Durand C, Peeters M, Vanes L, Tybulewicz V, Dzierzak E.  2006.  An unexpected role for IL-3 in the embryonic development of hematopoietic stem cells.Dev Cell. 11(2):171-80.
2005
Tavian M, Zheng B, Oberlin E, Crisan M, Sun B, Huard J, Péault B.  2005.  The vascular wall as a source of stem cells.Ann N Y Acad Sci. 1044:41-50.
2004
Ling K-W, Ottersbach K, van Hamburg JPiet, Oziemlak A, Tsai F-Y, Orkin SH, Ploemacher R, Hendriks RW, Dzierzak E.  2004.  GATA-2 plays two functionally distinct roles during the ontogeny of hematopoietic stem cells.J Exp Med. 200(7):871-82.
2002
de Bruijn MFTR, Ma X, Robin C, Ottersbach K, Sanchez M-J, Dzierzak E.  2002.  Hematopoietic stem cells localize to the endothelial cell layer in the midgestation mouse aorta.Immunity. 16(5):673-83.
Kumaravelu P, Hook L, Morrison AM, Ure J, Zhao S, Zuyev S, Ansell JD, Medvinsky A.  2002.  Quantitative developmental anatomy of definitive haematopoietic stem cells/long-term repopulating units (HSC/RUs): role of the aorta-gonad-mesonephros (AGM) region and the yolk sac in colonisation of the mouse embryonic liver.Development. 129(21):4891-9.
Oostendorp RAJ, Harvey KN, Kusadasi N, de Bruijn MFTR, Saris C, Ploemacher RE, Medvinsky A, Dzierzak E.  2002.  Stromal cell lines from mouse aorta-gonads-mesonephros subregions are potent supporters of hematopoietic stem cell activity.Blood. 99(4):1183-9.
1998
Dzierzak E, Medvinsky A, de Bruijn MFTR.  1998.  Qualitative and quantitative aspects of haematopoietic cell development in the mammalian embryo.Immunol Today. 19(5):228-36.
1996
Medvinsky A, Dzierzak E.  1996.  Definitive hematopoiesis is autonomously initiated by the AGM region.Cell. 86(6):897-906.
Medvinsky AL, Gan OI, Semenova ML, Samoylina NL.  1996.  Development of day-8 colony-forming unit-spleen hematopoietic progenitors during early murine embryogenesis: spatial and temporal mapping.Blood. 87(2):557-66.

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