CRM Publications

Easterbrook J, Rybtsov S, Gordon-Keylock S, Ivanovs A, Taoudi S, Anderson RA, Medvinsky AL.  2019.  Analysis of the Spatiotemporal Development of Hematopoietic Stem and Progenitor Cells in the Early Human Embryo.Stem Cell Reports. 12(5):1056-1068.

Becker CElizabeth, Quinn TJ, Williams AC.  2019.  Association Between Endothelial Cell Stabilizing Medication and Small Vessel Disease Stroke: A Case-Control Study

Narraway C, Davis O, Lowell S, Lythgoe KA, Turner SJ, Marshall S.  2019.  Biotic analogies for self-organising cities

Hess S, Rambukkana A.  2019.  Cell Biology of Intracellular Adaptation of in the Peripheral Nervous System.Microbiol Spectr. 7(4)

Illingworth R.  2019.  Chromatin folding and nuclear architecture: PRC1 function in 3D.Curr Opin Genet Dev. 55:82-90.

Flyamer IM, Illingworth R, Bickmore WA.  2019.  Coolpup.py – a versatile tool to perform pile-up analysis of Hi-C data

Eigel D, Zoupi L, Sekizar S, Welzel PB, Werner C, Williams AC, Newland B.  2019.  Cryogel scaffolds for regionally constrained delivery of lysophosphatidylcholine to central nervous system slice cultures: A model of focal demyelination for multiple sclerosis research.Acta Biomater.

Mansell E, Zareian N, Malouf C, Kapeni C, Brown N, Badie C, Baird D, Lane J, Ottersbach K, Blair A et al..  2019.  DNA damage signalling from the placenta to foetal blood as a potential mechanism for childhood leukaemia initiation.Sci Rep. 9(1):4370.

McLaughlin KA, Flyamer IM, Thomson JP, Mjoseng HK, Shukla R, Williamson I, Grimes GR, Illingworth R, Adams IR, Pennings S.  2019.  DNA methylation directs polycomb-dependent 3D genome re- organisation in naive pluripotency

Pantier R, Tatar T, Colby D, Chambers I.  2019.  Endogenous epitope-tagging of , and identifies TET2 as a naïve pluripotency marker.Life Sci Alliance. 2(5)

Ottersbach K.  2019.  Endothelial-to-haematopoietic transition: an update on the process of making blood.Biochem Soc Trans. 47(2):591-601.

Aloia L, McKie MAlexander, Vernaz G, Cordero-Espinoza L, Aleksieva N, van den Ameele J, Antonica F, Font-Cunill B, Raven A, Cigliano RAiese et al..  2019.  Epigenetic remodelling licences adult cholangiocytes for organoid formation and liver regeneration.Nat Cell Biol. 21(11):1321-1333.

Malouf C, Ottersbach K.  2019.  Fetal liver Mll-AF4+ hematopoietic stem and progenitor cells respond directly to poly(I:C), but not to a single maternal immune activation.Exp Hematol.

Jääger K, Simpson D, Kalantzaki M, Salzano A, Chambers I, Chandra T.  2019.  G2M splits mouse embryonic stem cells into naïve and formative pluripotency statesBioRxiv.

Fitch SR, Kapeni C, Tsitsopoulou A, Wilson NK, Göttgens B, de Bruijn MF, Ottersbach K.  2019.  Gata3 targets Runx1 in the embryonic haematopoietic stem cell niche.IUBMB Life.

Lopez-Yrigoyen M, Yang C-T, Fidanza A, Cassetta L, A Taylor H, McCahill A, Sellink E, Von Lindern M, van den Akker E, Mountford JC et al..  2019.  Genetic programming of macrophages generates an in vitro model for the human erythroid island niche.Nat Commun. 10(1):881.

Cassetta L, Fragkogianni S, Sims AH, Swierczak A, Forrester LM, Zhang H, Soong DYH, Cotechini T, Anur P, Lin EY et al..  2019.  Human Tumor-Associated Macrophage and Monocyte Transcriptional Landscapes Reveal Cancer-Specific Reprogramming, Biomarkers, and Therapeutic Targets.Cancer Cell.

Malaguti M, Migueles RPortero, Blin G, Lin C-Y, Lowell S.  2019.  Id1 Stabilizes Epiblast Identity by Sensing Delays in Nodal Activation and Adjusting the Timing of Differentiation

Bardile CFerrari, Garcia-Miralles M, Caron NS, Rayan NArul, Langley SR, Harmston N, Rondelli AMaria, Teo RTang Yi, Waltl S, Anderson LM et al..  2019.  Intrinsic mutant HTT-mediated defects in oligodendroglia cause myelination deficits and behavioral abnormalities in Huntington disease.Proc Natl Acad Sci U S A. 116(19):9622-9627.

Calabrese D, Roma G, Bergling S, Carbone W, Mele V, Nuciforo S, Fofana I, Campana B, Szkolnicka D, Hay DC et al..  2019.  Liver biopsy derived induced pluripotent stem cells provide unlimited supply for the generation of hepatocyte-like cells.PLoS One. 14(8):e0221762.

Wisniewski D, Lowell S, Blin G.  2019.  Mapping the Emergent Spatial Organization of Mammalian Cells using Micropatterns and Quantitative Imaging.J Vis Exp. (146)

Punovuori K, Migueles RPortero, Malaguti M, Blin G, Macleod K, Carragher NO, Pieters T, van Roy F, Stemmler MP, Lowell S.  2019.  N-cadherin stabilises neural identity by dampening anti-neural signals

Blin G, Sadurska D, Migueles RPortero, Chen N, Watson JA, Lowell S.  2019.  Nessys: A new set of tools for the automated detection of nuclei within intact tissues and dense 3D cultures.PLoS Biol. 17(8):e3000388.

Carpino G, Nevi L, Overi D, Cardinale V, Lu W-Y, Di Matteo S, Safarikia S, Berloco PBartolomeo, Venere R, Onori P et al..  2019.  Peribiliary Gland Niche Participates in Biliary Tree Regeneration in Mouse and in Human Primary Sclerosing Cholangitis.Hepatology.

Yolland L, Burki M, Marcotti S, Luchici A, Kenny FN, Davis JRobert, Serna-Morales E, Müller J, Sixt M, Davidson A et al..  2019.  Persistent and polarized global actin flow is essential for directionality during cell migration.Nat Cell Biol. 21(11):1370-1381.