CRM Publications

Flyamer IM, Illingworth R, Bickmore WA.  2019.  Coolpup.py – a versatile tool to perform pile-up analysis of Hi-C data

McLaughlin KA, Flyamer IM, Thomson JP, Mjoseng HK, Shukla R, Williamson I, Grimes GR, Illingworth R, Adams IR, Pennings S.  2019.  DNA methylation directs polycomb-dependent 3D genome re- organisation in naive pluripotency

Lopez-Yrigoyen M, Yang C-T, Fidanza A, Cassetta L, A Taylor H, McCahill A, Sellink E, Von Lindern M, van den Akker E, Mountford JC et al..  2019.  Genetic programming of macrophages generates an in vitro model for the human erythroid island niche.Nat Commun. 10(1):881.

Cassetta L, Fragkogianni S, Sims AH, Swierczak A, Forrester LM, Zhang H, Soong DYH, Cotechini T, Anur P, Lin EY et al..  2019.  Human Tumor-Associated Macrophage and Monocyte Transcriptional Landscapes Reveal Cancer-Specific Reprogramming, Biomarkers, and Therapeutic Targets.Cancer Cell.

Rashidi H, Luu N-T, Alwahsh SM, Ginai M, Alhaque S, Dong H, Tomaz RA, Vernay B, Vigneswara V, Hallett JM et al..  2018.  3D human liver tissue from pluripotent stem cells displays stable phenotype in vitro and supports compromised liver function in vivo.Arch Toxicol. 92(10):3117-3129.

Dillenburg A, Ireland G, Holloway RK, Davies CL, Evans FL, Swire M, Bechler ME, Soong D, Yuen TJ, Su GH et al..  2018.  Activin receptors regulate the oligodendrocyte lineage in health and disease.Acta Neuropathol. 135(6):887-906.

Senserrich J, Batsivari A, Rybtsov S, Gordon-Keylock S, Souilhol C, Buchholz F, Hills D, Zhao S, Medvinsky A.  2018.  Analysis of Runx1 Using Induced Gene Ablation Reveals Its Essential Role in Pre-liver HSC Development and Limitations of an In Vivo Approach.Stem Cell Reports. 11(3):784-794.

Row RH, Pegg A, Kinney BA, Farr GH, Maves L, Lowell S, Wilson V, Martin BL.  2018.  BMP and FGF signaling interact to pattern mesoderm by controlling basic helix-loop-helix transcription factor activity.Elife. 7

Buchtler S, Grill A, Hofmarksrichter S, Stöckert P, Schiechl-Brachner G, Gomez MRodriguez, Neumayer S, Schmidbauer K, Talke Y, Klinkhammer BM et al..  2018.  Cellular Origin and Functional Relevance of Collagen I Production in the Kidney.J Am Soc Nephrol. 29(7):1859-1873.

Bergholt MS, Serio A, McKenzie JS, Boyd A, Soares RF, Tillner J, Chiappini C, Wu V, Dannhorn A, Takats Z et al..  2018.  Correlated Heterospectral Lipidomics for Biomolecular Profiling of Remyelination in Multiple Sclerosis.ACS Cent Sci. 4(1):39-51.

Vasiliauskaite L, Berrens RV, Ivanova I, Carrieri C, Reik W, Enright AJ, O'Carroll D.  2018.  Defective germline reprogramming rewires the spermatogonial transcriptome.Nat Struct Mol Biol. 25(5):394-404.

Ballarino M, Cipriano A, Tita R, Santini T, Desideri F, Morlando M, Colantoni A, Carrieri C, Nicoletti C, Musarò A et al..  2018.  Deficiency in the nuclear long noncoding RNA causes myogenic defects and heart remodeling in mice.EMBO J. 37(18)

Hay DC, O'Farrelly C.  2018.  Designer human tissue: coming to a lab near you.Philos Trans R Soc Lond B Biol Sci. 373(1750)

Hagbard L, Cameron K, August P, Penton C, Parmar M, Hay DC, Kallur T.  2018.  Developing defined substrates for stem cell culture and differentiation.Philos Trans R Soc Lond B Biol Sci. 373(1750)

Blanchard GB, Fletcher AG, Schumacher LJ.  2018.  The devil is in the mesoscale: Mechanical and behavioural heterogeneity in collective cell movement.Semin Cell Dev Biol.

Mistri TKumar, Arindrarto W, Ng WPing, Wang C, Lim LHiong, Sun L, Chambers I, Wohland T, Robson P.  2018.  Dynamic changes in Sox2 spatio-temporal expression promote the second cell fate decision through/signaling in preimplantation mouse embryos.Biochem J. 475(6):1075-1089.

Dewari PSingh, Southgate B, Mccarten K, Monogarov G, O'Duibhir E, Quinn N, Tyrer A, Leitner M-C, Plumb C, Kalantzaki M et al..  2018.  An efficient and scalable pipeline for epitope tagging in mammalian stem cells using Cas9 ribonucleoprotein.Elife. 7

Zhang M, Leitch HG, Tang WWC, Festuccia N, Hall-Ponsele E, Nichols J, M Surani A, Smith A, Chambers I.  2018.  Esrrb Complementation Rescues Development of Nanog-Null Germ Cells.Cell Rep. 22(2):332-339.

Festuccia N, Halbritter F, Corsinotti A, Gagliardi A, Colby D, Tomlinson SR, Chambers I.  2018.  Esrrb extinction triggers dismantling of naïve pluripotency and marks commitment to differentiation.EMBO J. 37(21)

Malouf C, Ottersbach K.  2018.  The fetal liver lymphoid-primed multipotent progenitor provides the prerequisites for the initiation of t(4;11) MLL-AF4 infant leukemia.Haematologica.

Ward C, Volpe G, Cauchy P, Ptasinska A, Almaghrabi R, Blakemore D, Nafria M, Kestner D, Frampton J, Murphy G et al..  2018.  Fine-Tuning Mybl2 Is Required for Proper Mesenchymal-to-Epithelial Transition during Somatic Reprogramming.Cell Rep. 24(6):1496-1511.e8.

Barakat TStefan, Halbritter F, Zhang M, Rendeiro AF, Perenthaler E, Bock C, Chambers I.  2018.  Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells.Cell Stem Cell. 23(2):276-288.e8.

Blin G, Wisniewski D, Picart C, Théry M, Puceat M, Lowell S.  2018.  Geometrical confinement controls the asymmetric patterning of brachyury in cultures of pluripotent cells.Development. 145(18)

Crosby A, Toshner MR, Southwood MR, Soon E, Dunmore BJ, Groves E, Moore S, Wright P, Ottersbach K, Bennett C et al..  2018.  Hematopoietic stem cell transplantation alters susceptibility to pulmonary hypertension in Bmpr2-deficient mice.Pulm Circ. 8(4):2045894018801642.

Russell JO, Lu W-Y, Okabe H, Abrams M, Oertel M, Poddar M, Singh S, Forbes SJ, Monga SP.  2018.  Hepatocyte-specific β-catenin deletion during severe liver injury provokes cholangiocytes to differentiate into hepatocytes.Hepatology.